PDRN (Polynucleotides) | Cellular biostimulation, structural restoration and regeneration

Drawing on the latest advances in aesthetic medicine, we've introduced PDRN (polynucleotides) into our skincare routine—bioactive nucleic acid fragments that act as an intelligent repair code for damaged cells. This isn't a standard anti-aging treatment; it's deep, structural tissue regeneration at the DNA level. PDRN immediately stimulates fibroblasts to increase collagen and elastin production, drastically improving skin density, soothing inflammation, and reducing persistent microdamage. In the HDRÈY line, PDRN products are designed to work in synergy with other active ingredients (copper peptide, collagen). This is a highly concentrated treatment for skin requiring immediate, non-invasive transformation. Build a routine based on scientifically proven effectiveness and treat your skin to the highest level of cellular renewal.

FAQ - Frequently Asked Questions

What is PDRN (polynucleotides) and how does it affect the skin?

PDRN, or polynucleotides, are selected nucleic acid fragments that function as a natural repair code. They stimulate fibroblasts to produce new supporting fibers, activate cellular renewal, support the repair of UV-induced damage, and enhance microcirculation, leading to better tissue oxygenation and nourishment.

What are the primary benefits of PDRN biostimulation skincare?

Skincare powered by PDRN biostimulation leaves the skin noticeably denser, more elastic, and resilient against external aggressors. Additionally, it soothes micro-inflammation, restores a well-rested glow, and gradually rebuilds internal volume and tightness by stimulating fibroblasts to synthesize fresh collagen.

What active ingredients, besides PDRN, can be found in cellular biostimulation products?

Beyond PDRN, cellular biostimulation products feature active ingredients such as the Collagen 9D Complex (nine forms of collagen), Copper Peptide, the Renaissance HPS3® Complex, Hyaluronic Acid (in four forms), Trehalose, Betaine, and Caffeine in the eye serum. Formulas are further enriched with argan oil, mango seed butter, shea butter, and algae (spirulina).

Which skin types are polynucleotide and copper peptide formulations designed for?

These formulations are an exceptional choice for women whose skin requires specialized attention, deep hydration, and regenerative support. They are dedicated to mature skin that has lost density and firmness, while also benefiting younger complexions showing early signs of fatigue or dullness. Furthermore, they are well-tolerated by delicate skin needing soothing repair after sun or wind exposure.

How to properly apply polynucleotide products in a daily skincare ritual?

The morning ritual begins with cleansing, followed by the Restorative Anti-Wrinkle Serum with PDRN, an eye cream or emulsion, and finishes with the Restorative Day Anti-Wrinkle Cream. In the evening, after makeup removal, reapply the face serum and eye product, followed by the Restorative Night Anti-Wrinkle Cream. Complement the ritual 1–2 times a week with Collagen 9D Firming-Regenerating Hydrogel Masks.